Jin Li;Rui Song;Hui Zhu;Rusheng Zhao;Liuhong Yun;Rifang Yang;Ning Wu;Ruibin Su
发明人:
Jin Li,Rifang Yang,Rui Song,Hui Zhu,Ning Wu,Liuhong Yun,Ruibin Su,Rusheng Zhao
申请号：
US13123368
公开号：
US08829001B2
申请日:
2009.09.28
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson's disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.
