COMPOSITIONS FOR TREATMENT OF SKIN WOUND COMPRISING TRANSFORMING GROWTH FACTOR BETA-INDUCED PROTEIN AS ACTIVE INGREDIENT农业专利-农业学术服务平台

专利权人:: 연세대학교 산학협력단; YONSEI UNIVERSITY;INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY;INDUSTRY-ACADEMIC COOPERATION FOUNDATION

发明人:: MAENG, YONG SUN,맹용선,KIM, EUNG KWEON,김응권,MAENG, YONG SUNKR,KIM, EUNG KWEONKR

摘要：: Provided in the present invention is a composition for treating skin wound including transforming growth factor beta induced (TGFBI) protein as an active ingredient. The composition of the present invention has a wound treating ability by increasing mobility and tube formation in a lymphatic vessel endothelial cell. The composition of the present invention may be manufactured as a pharmaceutical composition, a cosmeceutical composition, or a cosmetic composition. Also provided in the present invention is a screening method of a wound treating formation.본 발명은 TGFBI 단백질을 유효성분으로 포함하는 피부 손상 치료용 조성물을 제공한다. 본 발명의 조성물은 림프관 내피세포의 이동성 및 관형성을 증가시킴으로써 상처치유능을 나타낸다. 본 발명의 조성물은 약제학적 조성물, 기능성화장료(cosmeceutical) 조성물 또는 화장료 조성물로 제조될 수 있다. 또한, 본 발명은 상처 치유 제제의 스크리닝 방법을 제공한다.