High-affinity fully functional soluble single-domain human CD4, antibodies, and related fusion proteins

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专利权人:

Dimiter S. Dimitrov

发明人:

Dimiter S. Dimitrov,Weizao Chen

申请号：

US13699535

公开号：

US08911728B2

申请日:

2011.05.20

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The invention provides engineered antibody domains (eAds), a polypeptide comprising a single domain CD4, as well as a fusion protein comprising the same. Nucleic acids encoding eAd and/or polypeptide or the fusion protein thereof, as well as compositions or cells comprising the eAd, polypeptide, fusion protein, or nucleic acid also are provided.

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