Joseph Itskovitz-Eldor,Bettina Fishman,Hanna Segev
申请号：
US13640532
公开号：
US08927274B2
申请日:
2011.04.12
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method of generating pancreatic progenitor cells is disclosed. The method comprises:(a) differentiating stem cells under conditions such that at least a portion of the cells express glucose transporter 2 (GLUT2) so as to generate GLUT2-expressing cells and(b) enriching for the GLUT2-expressing cells so as to generate a population of GLUT2 enriched cells, wherein at least 80% of the population of GLUT2 enriched cells express GLUT2, thereby generating pancreatic progenitor cells.Isolated populations of cells generated according to the method, pharmaceutical compositions comprising same and uses thereof are also disclosed.
