HIGUCHI, ROBERT I. I,羅伯特‧,ROBERTS, TUCKER CURRAN,‧希古奇,SMITH, PETER ANDREW,塔克‧柯倫‧羅伯茨,CAMPBELL, DAVID,彼得‧安德魯‧史密斯,PARASELLI, PRASUNA,大衛‧坎貝爾,普拉蘇納‧帕拉塞利
申请号：
HK15106179.3
公开号：
HK1205736A
申请日:
2015.06.29
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
