compound, pharmaceutical composition, kit, methods for inhibiting a jak kinase activity, for treating a disease, for treating allograft transplant rejection in a transplant recipient, for treating a hypersensitivity reaction, and for inhibiting a transduction cascade signal and compound use
DARREN JOHN MCMURTRIE,HUI LI,PINGYU DING,RAJINDER SINGH,ROSE YEN,SAMBAIAH THOTA,THILO J. HECKRODT,VANESSA TAYLOR,YAN CHEN
申请号:
BRPI1006942
公开号:
BRPI1006942A2
申请日:
2010.01.22
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful.