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NOVEL CARBOCYCLIC COMPOUNDS AS ROR GAMMA MODULATORS
专利权人:
发明人:
DAS SANJIB,GHARAT LAXMIKANT ATMARAM,HARDE RAJENDRA LAXMAN,SHELKE DNYANESHWAR EKNATH,PARDESHI SHAILESH RAMESH,THOMAS ABRAHAM,KHAIRATKAR JOSHI NEELIMA,SHAH DAISY MANISH,BAJPAI MALINI
申请号:
IN201827006774
公开号:
IN201827006774A
申请日:
2018.02.22
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present disclosure is directed to novel carbocyclic compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R1 R2 R3 R4 R5 R6 Ra Rb n m and p are as defined herein which are active as modulators of retinoid related orphan receptor gamma t (RORt). These compounds prevent inhibit or suppress the action of RORt and are therefore useful in the treatment of RORt mediated diseases disorders syndromes or conditions such as e.g. pain inflammation COPD asthma rheumatoid arthritis colitis multiple sclerosis psoriasis neurodegenerative diseases and cancer.
来源网站:
中国工程科技知识中心
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