The invention relates to a self-propelled machine for agriculture, having a support structure (T) which receives various attachment devices (2), has at least one drive assembly (3) having a control module (4), is movable by means of ground supports (B, B') on the end, and forms an agricultural gantry system, having at least one base carrier (6), for variable work tasks, which gantry system, proceeding from a road orientation defining a travel width (dimension FB), can be converted to a working orientation having a substantially larger working width (AB), wherein the support structure (T) has lateral carriers (ST, ST') comprising the ground supports (B, B'). The support structure defining a longitudinal orientation in the road orientation has, in the region of its two ground supports (B, B') on the end thereof, a vertical longitudinal center plane (M) extending therebetween. In spatial orientation thereto, a functional frame (FR, FR') having an asymmetrical base carrier (6') is proposed as a support structure. According to the invention, the base carrier (6), proceeding from the longitudinal dimension (FB) of the possible travel width(s), is connected to the at least one lateral carrier (ST, ST') in an outer third (TD, TD') of said longitudinal dimension (FB).