A splint for immobilization of a limb of a patient. The splint includes an outer immobilization construct extending in a longitudinal direction of the limb, an inner immobilization construct in contact with the limb, a splint binder binding the outer immobilization construct in place around the second wrapping construct, and an expandable air cuff disposed between the outer immobilization construct and the second immobilization construct, which upon inflation exerts pressure on the second immobilization construct to conform the inner immobilization construct to the limb. With the splint, a method for immobilizing the limb includes placing a conformable restraint over the limb, securing an inflatable air cuff over the conformable restraint, and pressurizing the inflatable air cuff to thereby exert a controlled pressure on the limb.