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An improved receiver format combined with antigens
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
KLEIN, Christian,MOESSNER, Ekkehard,DAROWSKI, Diana,STUBENRAUCH, Kay-Gunnar
申请号:
PE2019001939
公开号:
PE20191703A1
申请日:
2018.03.26
申请国别(地区):
PE
年份:
2019
代理人:
摘要:
The current invention refers to a new way to designate tumor related antigens by a receptor combined with antigens. More specifically, the present invention refers to an antiviral alliance receiver, which effectively binds / interacts with an antigen on the surface of tumor cells, and connects / interacts with an alliance antiviral receiver. In addition,The invention refers to a nucleic acid molecule and a coding carrier polymerized into an antibody receiver. The invention also provides for the production and use of T cells in methods for the treatment of specific diseases, as well as drugs for the composition of pharmacology, including receptors for the combination of antiretroviral and / or T cells.La presente invencion se refiere a receptores de union a antigeno en formatos nuevos capaces de union especifica a un antigeno asociado a tumor. Mas exactamente, la presente invencion se refiere a un receptor de union a antigeno que se une/interactua eficiente y especificamente con un antigeno sobre la superficie de una celula tumoral, y con una celula T transfectada/transducida con el receptor de union a antigeno. Ademas, la invencion se refiere a moleculas de acidos nucleicos y vectores codificantes de receptores de union a antigeno de la presente invencion. La invencion proporciona ademas la produccion y utilizacion de celulas T en un metodo para el tratamiento de enfermedades particulares, asi como composiciones/medicamentos farmaceuticos que comprenden receptores de union a antigeno y/o celulas T de la presente invencion
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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