Fleischer Jesper,Hasenkam Michael,Magnusson Nils E.,Nygaard Hans
申请号：
US201414785746
公开号：
US10094824(B2)
申请日:
2014.04.25
申请国别(地区):
美国
年份:
2018
代理人:
Dinsmore & Shohl LLP
摘要：
The present invention concerns a device for measuring the concentration of analytes in liquid samples such as bodily samples. The device comprises an application zone, to which a sample can be applied, and which contains a specific molecule capable of specifically binding the analyte of interest, said specific molecule being conjugated to a reporter which can give rise to variations in impedance. The resulting complex migrates by capillarity and enters a detection zone, on which another molecule capable of specifically binding the analyte of interest is immobilized. The concentration of reporter molecules in the detection zone is proportional with the concentration of analyte in the sample, and variations in concentration of reporter molecules yield a measurable change in electrical properties such as a change in impedance and/or capacitance which can be correlated to the concentration of analyte. The device is useful for monitoring concentrations of analytes that are biological markers for bacterial, viral o
