Bartra Sanmarti, Marti,Berenguer Maimo, Ramon,Benet-Buchholz, Jordi,Sola i Carandell, Lluis
申请号:
HUE14198021
公开号:
HUE037892T2
申请日:
2009.01.21
申请国别(地区):
HU
年份:
2018
代理人:
摘要:
Crystalline form of abacavir of formula (I), its preparation process which comprises the following steps: a) crystallizing abacavir from a solution of said compound in a (C 1 -C 4 )-alcohol, dichloromethane, acetonitrile/water, or mixtures thereof; b) isolating the crystalline form of abacavir that appears in the prior step; and c) removing the solvent from the crystalline form of abacavir thus obtained. It can also be obtained by dispersion of abacavir in acetonitrile. It is useful for the preparation of pharmaceutical compositions for use in the treatment and/or prophylaxis of HIV infections.