Drug delivery device comprising: - a housing (10) adapted to receive a container (24) of drug with or without an element (28) connectable administration - a mechanism (90) drive on which it acts and which in turn acts on the container (24) of medication - an element (48) movable activation from a first position, in which it allows the mechanism (90) drive to be retained, to a second position, which allows the mechanism (90) for actuating release of way that allows the drug to be ejected through the element (28) of administration - an element (46) movable locking between a locking position, which prevents movement of the element (48) of activation from its first position to its second position, and a release position, which allows movement of element (48) of activation from its first position to its second position, the device having an indicator to show that it has been used for being retained provided element (48) activation in its second position wherein the activation element comprises at least one projection (58) engaging and actuating mechanism comprises surfaces (64) corresponding engagement against the projections (58) engaging hook when the element (48) activation is in its second position.Dispositivo de administración de medicamento que comprende: - un alojamiento (10) adaptado para recibir un recipiente (24) de medicamento con o sin un elemento (28) de administración conectable - un mecanismo (90) de accionamiento sobre el que se actúa y que a su vez actúa sobre el recipiente (24) de medicamento - un elemento (48) de activación móvil desde una primera posición, en la que permite que el mecanismo (90) de accionamiento se retenga, hasta una segunda posición, en la que permite que el mecanismo (90) de accionamiento se libere, de manera que se permite que el medicamento se expulse a través del elemento (28) de administración - un elemento (46) de enclavamiento móvil entre una posición de bloqueo, en la que impide el movimiento del elemento (48) de activación d
