Tiberiu Mircea Siclovan,Cristina Abucay Tan Hehir,Rong Zhang,Victoria Eugenia Cotero,Anshika Bajaj
申请号:
US13689819
公开号:
US20140154178A1
申请日:
2012.11.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method and a kit for detecting myelin basic protein are provided. The method comprises administering an agent, which binds to myelin basic protein (MBP), to a subject at risk of or diagnosed with a myelin-associated neuropathy, and determining myelination by detecting the agent resided in the subject. The amount of the agent present in the subject is indicative of a myelin-associated neuropathy. A method of quantifying an amount of MBP present in a tissue sample is also provided, wherein the method comprises contacting the tissue sample with the same agent, detecting the agent present in the tissue sample and quantifying an amount of the agent present in the tissue sample.