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МЕМБРАННЫЙ БЕЛОК МИКРОВЕЗИКУЛ И ЕГО ПРИМЕНЕНИЕ
专利权人:
ЦЗЯН Мин-Чун
发明人:
ЦЗЯН Мин-Чун
申请号:
RU2014110231
公开号:
RU2014110231A
申请日:
2011.08.18
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method for in vitro protein level measurement CSE1L (chromosome segregation 1-like) or phosphorylated CSE1L microvesicles in a sample of biological fluid obtained from the subject, characterized in that said method includes the step of contacting an antibody against microvesicles CSE1L or anti phosphorylated CSE1L.2. The method of claim. 1, characterized in that the amount of phosphorylated or CSE1L CSE1L measured by analysis of said sample using the method of the dot-blot.3. A method according to claim 1, characterized in that the amount of CSE1L is measured by assessing binding of the antibody against CSE1L and microvesicles. and the amount of phosphorylated CSE1L is measured by assessing binding of the antibody against phosphorylated and CSE1L mikrovezikul.4. The method of claim. 1, characterized in that said subject is a cheloveka.5. in vitro method of measuring the levels of phosphorylated CSE1L in a sample of biological fluid obtained from the subject, characterized in that said method comprises the step of contacting the sample with an antibody that recognizes phosphorylated CSE1L.6. The method of claim. 5, characterized in that the amount of phosphorylated CSE1L measured by analysis of said sample by enzyme linked immunosorbent assay (ELISA) .7. The method of claim. 5, characterized in that the amount of phosphorylated CSE1L measured by analysis of antibody binding against phosphorylated to the phosphorylated CSE1L CSE1L.8. The method of claim. 5, characterized in that said subject is a cheloveka.9. A pharmaceutical composition for targeting a tumor, characterized in that said pharmaceutically1. Способ измерения in vitro уровня белка CSE1L (chromosome segregation 1-like) или фосфорилированного CSE1L в микровезикулах в образце биологической жидкости, полученного от субъекта, характеризующийся тем, что указанный способ включает в себя стадию осуществления контакта микровезикул с антителом против CSE1L или антителом против фосфорилированного CSE1L.2. Спосо
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