Tang, Jiansheng,Deverich, Joseph M.,Miller II, Kenneth J.,Beste, Russell D.
申请号：
AU2009302853
公开号：
AU2009302853B2
申请日:
2009.10.01
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention refers to a transdermal delivery device comprising a backing layer, an adhesive matrix layer comprising a supersaturated concentration of rotigotine substantially in amorphous form within the adhesive matrix, and a release liner. The present invention also refers to a method of preparing an adhesive matrix containing a supersaturated amount of rotigotine substantially in amorphous form. Further, the present invention refers to a method of stabilizing and a method of reestablishing the meta-stable amorphous-drug transdermal system during its manufacturing, storing, shipping and handling process.
