A toothbrush includes a brush head having a capsule receiving zone sized to receive a dentrifice capsule. A plurality angled bristles may retain the capsule in such zone. Loading of such toothbrush with a capsule may be performed with a dispenser including a toothbrush manipulation element adapted to move a retention structure associated with the brush head, and dispensation element adapted to deliver the capsule into the receiving zone. Such dispenser may include a desiccant material disposed to receive moisture from a capsule storage container. A dispenser may further include a plurality of toothbrush insertion apertures each adapted to receive a portion of a different toothbrush, so as to enable multiple users each having different toothbrushes to use the same dispenser without requiring contact between multiple brushes and single capsule interface surface of the dispenser.
