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Benzotiofenski derivati in njihovi sestavki kot selektivni razgrajevalci estrogenskega receptorja
专利权人:
Novartis AG
发明人:
BURKS Heather Elizabeth,DECHANTSREITER Michael A.,HE Guo,NUNEZ Jill,PEUKERT Stefan,SPRINGER Clayton,SUN Yingchuan,THOMSEN Noel Marie-France,TRIA George Scott,YU Bing
申请号:
SI201430679
公开号:
SI2958907T1
申请日:
2014.02.12
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
The present invention relates to compounds of formula I: in which n, m, X, Y 1 , R 1 , R 2 , R 3 , R 4 and R 5 are defined in the Summary of the Invention; capable of being both potent antagonists and degraders of estrogen receptors. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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