An arterial pulse signal measurement device includes a pressure sensor and a measuring apparatus. When the pressure sensor is attached to the skin, stratum corneum or other superficial organs of a human body or animal body, and a constant voltage is applied to first voltage input terminal (V+) and a second voltage input terminal (V−；) of the pressure sensor, the pressure sensor will output a corresponding voltage signal to the measuring apparatus according to the arterial pulse of the human body or animal body. The measuring apparatus will acquire the arterial pulse signal of the human body or animal body according to the voltage signal.
