Measurement device and method for noninvasive determination of at least one physiological parameter, the device comprising a diagnostic sensor unit (1) for generating measurement signals, and an evaluation unit for processing the measurement signals. The diagnostic sensor unit (1) comprises at least one pressure sensor (3) which detects the pressure exerted locally onto the pressure sensor (3) by a body tissue which is to be examined. The evaluation unit is configured to derive at least one physiological parameter from the measurement signal of the pressure sensor (3).