This creation provides a kind of inhibition oral cavity and causes a disease the bedded structure of primary long probiotics long-effect active constituent,It includes one surpassing separation layer,The outer surface of the bedded structure of system's setting what constituent; One stabilized zone,System directly pastes the inner surface of the connection what super separation layer; One victory peptide layer,System directly pastes the inner surface of the connection what stabilized zone; One active series of strata system directly pastes the inner surface of the connection what victory peptide layer; Wherein,The outer surface of the super separation layer and inner surface are formed with the wave flange of series or more extension,Make the stabilized zone,Victory peptide layer and active layer are also formed with the wave flange of series or more extension,Simultaneously one of lift structure intensity multi-layer solid dosage form can be collectively formed.本創作提供一種抑制口腔致病原生長之益生菌長效活性組成物之層狀構造,其包括一超隔離層,係設置於該組成物之層狀構造之外表面;一穩定層,係直接貼覆連接於該超隔離層之內表面;一胜肽層,係直接貼覆連接於該穩定層之內表面;一活性層係係直接貼覆連接於該胜肽層之內表面;其中,該超隔離層之外表面與內表面形成有系列上下延伸之波浪凸緣,使該穩定層、胜肽層和活性層亦形成有系列上下延伸之波浪凸緣,以能共同構成並提升結構強度之一多層固體劑型。