Antonio Nardi,Jeppe Kejser Christensen,Dan Peters,Tino Dyhring
申请号:
US12743836
公开号:
US08101649B2
申请日:
2008.11.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to N-acylhydrazone derivatives, which are found to be useful as modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.