Gunnar M. Olsen;Elsebet Østergaard Nielsen;Dan Peters;Daniel B Timmermann;Steven Charles Loechel
发明人:
Dan Peters,Gunnar M. Olsen,Elsebet Østergaard Nielsen,Daniel B Timmermann,Steven Charles Loechel
申请号：
US12299106
公开号：
US08148365B2
申请日:
2007.05.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention relates to a novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its use in the manufacture of pharmaceutical compositions. The compound of the invention is found to be a cholinergic ligand at the nicotinic acetylcholine receptors.Due to its pharmacological profile the compound of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
