A disinfestation sheet includes a carrier layer with active pesticidal particles formed therein. The active pesticidal particles contain pesticidal ingredients selected from pyrethroid family or the like. Pyrethroids may be produced and prepared after plant extracts. The carrier layer has channels formed therein. The channels form one or more paths between one or more pesticidal particles and at least one of the first and the second surfaces to allow diffusion of the active pesticidal ingredient from the pesticidal particles to at least one of the first and the second surfaces of the carrier layer. When pests move to become in contact with a disinfestation sheet, the pesticidal ingredient reacts with the pests’ integral membrane protein, hindering the nerve cells and associated functions, eventually ceasing the functions of nerve cells and killing the pests within short period time.一種滅蟲片包括其中形成有活性殺蟲粒子的載體層。活性殺蟲粒子含有選自擬除蟲菊酯族等的殺蟲成分。擬除蟲菊酯可以由植物提取物生產和製備。載體層中形成有通道。通道在一個或多個殺蟲粒子及第一及第二表面中的至少一個間形成一個或多個路徑,以允許活性殺蟲成分從殺蟲粒子擴散到載體層的第一及第二表面中的至少一個表面。當害蟲與滅蟲片接觸時,殺蟲成分與害蟲膜主題蛋白反應,阻礙害蟲的神經細胞及相關功能,最終停止神經細胞的功能並在短時間內殺死害蟲。