Disclosed is a tramadol hydrochloride and paracetamol composition, comprising: about 2.5 to about 5 percent by weight of tramadol hydrochloride； about 25 to about 30 percent by weight of paracetamol； about 1.25 to about 1.75 percent by weight of colloidal silicon dioxide；about 0.25 to about 0.35 percent by weight of povidone K-30； about 4.5 to about 5.5 percent by weight of ethyl cellulose N7； about 1.5 to about 2 percent by weight of mannitol 25； about 20 to about 25 percent by weight of mannitol 400； about 20 to about 25 percent by weight of mannitol 35； about 9 to about 11 percent by weight of a disintegrant； about 3 to about 5 percent by weight of a sweetener； about 1 to about 1.5 percent by weight of a flavorant； and about 0.5 to about 1.5 percent by weight of a lubricant.
