Jeff Zablocki,Matthew Abelman,Michael Organ,Yaroslav Bilokin,Elfatih Elzein,Tetsuya Kobayashi,Rao Kalla,Thao Perry,Xiaofen Li,Robert Jiang,Ivan Diamond,Lina Yao,Peidong Fan,Maria Pia Arolfo,Zhan Jiang
申请号:
US12371398
公开号:
US08158810B2
申请日:
2009.02.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are novel isoflavone derivatives having the structure of Formula Iwhich are useful as ALDH-2 inhibitors for treating mammals for dependence upon drugs of addiction, for example addiction to dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and alcohol.