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RÉGÉNÉRATION OSSEUSE À MÉDIATION PAR DES ANTICORPS
专利权人:
ZADEH; HOMAYOUN H.
发明人:
ZADEH, HOMAYOUN H.
申请号:
EP10733825
公开号:
EP2389195A4
申请日:
2010.01.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention relates to the field of immunologically reactive molecules used to improve implantable medical devices. Immobilization of selected antibody molecules onto the surface of medical implants enable localization and concentration of in vivo growth factors in a timely manner to enhance the wound healing process following implantation of the device. When in vivo BMP-2 growth factor was captured on an implant device by attached monoclonal antibodies, the biological activity of BMP-2 was enhanced in the vicinity of the implant device. BMP-2 growth factor-specific antibody molecules or their fragments when immobilized on titanium dental or orthopedic implants improve osseo-integration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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