KI STIV,AKINSAN'JA KAREN O.,RIV'ER P'ER ZH.-M.,ZHJUN'EN ZHAN-LUI
申请号：
RU20030112700
公开号：
RU2305133(C2)
申请日:
2001.10.12
申请国别(地区):
俄罗斯
年份:
2007
代理人:
摘要：
FIELD: biotechnology, pharmacology, medicine. ^ SUBSTANCE: DNA sequence encoding of new kind of human serine protease (DPRP-2), is cloned and characterized, wherein said DPRP-2 is cognate to dipeptidyl oligopeptidase IV and hase gomology wherewith of 39 % determined using amino acid sequence. By using of recombinant DNA technologe recombinant form of DPRP-2 is obtained and kinetic properties of new enzyme (substrate specifity, Km values, activity inhibitors, etc.) are investigated. ^ EFFECT: new means for screening and development of new therapeutic agents for treatment of various deceases in human. ^ 4 cl, 7 dwg, 7 ex
