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Compuestos de organoarsenóxido y uso de los mismos
专利权人:
NEWSOUTH INNOVATIONS PTY LIMITED
发明人:
HOGG, PHILIP JOHN,DILDA, PIERRE
申请号:
ES07815480
公开号:
ES2411094T3
申请日:
2007.11.01
申请国别(地区):
ES
年份:
2013
代理人:
摘要:
A compound of general formula (I): ** ** Formula wherein: As (OH) 2 may be ortho, meta or para to the N atom of the phenyl ring R1 is selected from hydrogen and C1-3alkyl R2 and R3 may be the same or different and are independently selected from hydrogen, optionally substituted C1-3 alkyl, optionally substituted cyclopropyl, optionally substituted C2-3 alkenyl and optionally substituted C1-3 alkoxy R4 and R5 may be the same or different and are independently selected from hydrogen, optionally substituted C1-3 alkyl, optionally substituted cyclopropyl, optionally substituted C2-3 alkenyl and optionally substituted C1-3 alkoxy m is an integer selected from 1, 2 and 3 n is an integer selected from 1, 2 and 3 * Indicates a chiral carbon atom and salts and hydrates thereof wherein the optional substituent is independently selected from alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, halo, haloalkyl, haloalkynyl, hydroxyl, hydroxyalkyl, alkoxy, thioalkoxy, alkenyloxy, haloalkoxy, haloalkenyloxy, NO2, nitroalkyl, nitroalkenyl, nitroalkynyl, nitroheterocyclyl , alkylamino, dialkylamino, alkenylamino, alkynylamino, acyl, alkenoyl, alkynoyl, acylamino, diacylamino, acyloxy, alkylsulfonyloxy, heterocycloxy, heterocycloamino, haloheterocycloalkyl, alkylsulfenyl, alkylcarbonyloxy, alkylthio, acylthio, phosphono, phosphinyl, aryl, heteroaryl, alkylaryl, aralkyl, alkylheteroaryl , cyano, cyanate, isocyanate, CO2H, CO2, C (O) NH2, -C (O) NH (alkyl) and -C (O) N (alkyl) 2.Un compuesto de fórmula general (I): **Fórmula** donde: el grupo As(OH)2 puede estar orto, meta o para con respecto al átomo de N del anillo de fenilo R1 se selecciona de entre hidrógeno y alquilo C1-3 R2 y R3 pueden ser iguales o diferentes y se seleccionan independientemente de entre hidrógeno, alquilo C1-3 opcionalmente sustituido, ciclopropilo opcionalmente sustituido, alquenilo C2-3 opcionalmente sustituido y alcoxi C1-3 opcionalmente sustituido R4 y R5 pueden ser iguales o diferentes y se
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