A high throughput endo-illuminator and illumination surgical system aredisclosed. One embodiment of the high throughput endo-illumination surgicalsystem comprises: a light source for providing a light beam; a proximaloptical fiber, optically coupled to the light source for receiving andtransmitting the light beam; a distal optical fiber, optically coupled to adistal end of the proximal optical fiber, for receiving the light beam andemitting the light beam to illuminate a surgical site, wherein the distaloptical fiber comprises a tapered section having a proximal-end diameterlarger than a distal-end diameter; a handpiece, operably coupled to the distaloptical fiber; and a cannula, operably coupled to the handpiece, for housingand directing the distal optical fiber. The tapered section's proximal enddiameter can be the same as the diameter of the proximal optical fiber, andcan be, for example, a 20 gauge diameter. The tapered section's distal enddiameter can be, for example, a 25 gauge compatible diameter. The cannula canbe a 25 gauge inner-diameter cannula. The proximal optical fiber canpreferably have an NA equal to or greater than the NA of the light source beamand the distal optical fiber preferably can have an NA greater than that ofthe proximal optical fiber and greater than that of the light source beam atany point in the distal optical fiber (since the light beam NA can increase asit travels through the tapered section).