An endoluminal prosthesis assembly includes a delivery system having an introduction end, an operator end, and a stent graft retention region. An endoluminal prosthesis (22, 122, 222) is disposed at the stent graft retention region. The prosthesis (22, 122, 222) comprises a tubular body, an inner lumen extending between proximal and distal ends of the tubular body, at least one fenestration (30, 130, 230) disposed in a sidewall of the body, and an internal branch at least partially formed with the sidewall of the body and disposed in parallel alignment with the prosthesis (22, 122, 222). A guide wire (38, 138, 238) having a first end and a second end is pre-loaded with the prosthesis (22, 122, 222) in the delivery system. At least a portion of the guide wire (38, 138, 238) is disposed within the internal branch and the inner lumen of tubular body of the prosthesis (22, 122, 222) prior to delivery of the prosthesis (22, 122, 222) and during delivery and deployment of the prosthesis (22, 122, 222). The second end of the guide wire (38, 138, 238) extends distally from the distal opening of the tubular body, and the first end of the guide wire (38, 138, 238) extends through the internal branch and the at least one fenestration (30, 130, 230) such that a portion of the guide wire (38, 138, 238) is externally disposed relative to the prosthesis (22, 122, 222). The externally disposed portion of the guide wire is bent back on itself to form an externally disposed loop.
