Marian E. Fundytus;Donald J. Kyle;R. Richard Goehring
发明人:
Donald J. Kyle,R. Richard Goehring,Marian E. Fundytus
申请号:
US13055873
公开号:
US08530494B2
申请日:
2009.07.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to Buprenorphine Analog compounds of the Formula I, Formula II or Formula III shown below, wherein R1, R2, R8, R3, R3a, R3b, X, Z and Y are as defined herein.Compounds of the Invention are useful for treating pain and other conditions modulated by activity of opioid and ORL1 receptors.