Methods and kits are provided for reversibly affixing an implant to a sclera of an eye of a subject. The methods and kits are based on applying a composition comprising at least one fibrin-based tissue adhesive to at least one of said implant and said sclera, thereby affixing said implant to the sclera, and applying a composition comprising at least one plasminogen activator to at least one of said implant and said sclera following a desired time-period, thereby detaching said implant from said sclera, and removing said implant from said eye.