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AMINOPYRAZOLE DERIVATIVE
专利权人:
CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
TAKA, NAOKI,OHMORI, MASAYUKI,TAKAMI, KYOKO,MATSUSHITA, MASAYUKI,HAYASE, TADAKATSU,HYODO, IKUMI,KOCHI, MASAMI,NISHII, HIROKI,EBIIKE, HIROSATO,NAKANISHI, YOSHITO,MIO, TOSHIYUKI,WANG, LISHA,ZHAO, WEILI
申请号:
EP10806527
公开号:
EP2471786A4
申请日:
2010.08.05
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A compound represented by formula (I) or a pharmacologically acceptable salt thereof, which can inhibit a fibroblast growth factor receptor (FGFR) family kinase in cancer tissues. (In the formula, A represents a 5- to 10-membered heteroaryl group, or a C6-10 aryl group R1 and R2 independently represent H, OH, X, CN, NO2 a C1-4 haloalkyl group, a C1-6 alkyl group, or the like R3 represents H, a C1-5 alkyl group, a C6-10 aryl group, a C1-5 alkyl group, or a C1-4 haloalkyl group and R4 represents H, X, a C1-3 alkyl group, a C1-4 haloalkyl group, OH, CN, NO2 or the like.)
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