1. An expression system comprising the polynucleotides encoding the proteins, wherein the first expression system comprises a polynucleotide encoding at least one protein, peptide or variant thereof that induces T-cell response, and a second polynucleotide encoding at least one protein, peptide or their option, which induces B-cell response against patogena.2. An expression system according to Claim. 1, wherein the first polynucleotide and second polynucleotide are joined in such a way that they are expressed in the form of artificial poliproteina.3. An expression system according to Claim. 1, where the proteins, peptides or fragments thereof encoded by the first and second polynucleotide are separated co- or postranslyatsionno.4. An expression system according to claim. 2 or 3, wherein a polynucleotide encoding a cleavage site located between the first polynucleotide and the second polinukleotidom.5. The expression system according to claim. 4, wherein the cleavage site is represented by self-cleavage site or the cleavage site endopeptidazoy.6. An expression system according to Claim. 1 further comprising a third polynucleotide that encodes a protein or variant thereof, which preferably induces T cell otvet.7. An expression system according to Claim. 1 wherein the expression system comprises at least one vector which is selected from the group consisting of plasmid vectors, cosmid vectors, phage vectors, the vectors preferably from phage lambda and filamentous phage and viral vektorov.8. An expression system according to claim. 7, where the viral vector is selected from the group consisting of PanAd1, PanAd2, PanAd3, ChAd55, ChAd73, ChAd83, ChAd146, ChAd147, ChAd3, ChAd4, ChAd5, ChAd6, ChAd7, ChAd8, ChAd9, ChAd10, ChAd11, ChAd16, ChAd17, ChAd19, ChAd20, ChAd22, ChAd24, ChAd26, ChAd30, ChAd31, ChAd37, ChAd38, ChAd44,1. Экспрессионная система, содержащая полинуклеотиды, кодирующие белки, причем экспрессирующая система включает первый полинуклеотид, кодирующий по мень