您的位置: 首页 > 农业专利 > 详情页

ЭКСПРЕССИОННЫЕ СИСТЕМЫ
专利权人:
ОКАЙРОС АГ (CH)
发明人:
ВИТЕЛЛИ Алессандра (IT),НИКОЗИЯ Альфредо (IT),КОРТЕЗЕ Риккардо (CH)
申请号:
RU2013135498/10
公开号:
RU2013135498A
申请日:
2011.12.30
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. An expression system comprising the polynucleotides encoding the proteins, wherein the first expression system comprises a polynucleotide encoding at least one protein, peptide or variant thereof that induces T-cell response, and a second polynucleotide encoding at least one protein, peptide or their option, which induces B-cell response against patogena.2. An expression system according to Claim. 1, wherein the first polynucleotide and second polynucleotide are joined in such a way that they are expressed in the form of artificial poliproteina.3. An expression system according to Claim. 1, where the proteins, peptides or fragments thereof encoded by the first and second polynucleotide are separated co- or postranslyatsionno.4. An expression system according to claim. 2 or 3, wherein a polynucleotide encoding a cleavage site located between the first polynucleotide and the second polinukleotidom.5. The expression system according to claim. 4, wherein the cleavage site is represented by self-cleavage site or the cleavage site endopeptidazoy.6. An expression system according to Claim. 1 further comprising a third polynucleotide that encodes a protein or variant thereof, which preferably induces T cell otvet.7. An expression system according to Claim. 1 wherein the expression system comprises at least one vector which is selected from the group consisting of plasmid vectors, cosmid vectors, phage vectors, the vectors preferably from phage lambda and filamentous phage and viral vektorov.8. An expression system according to claim. 7, where the viral vector is selected from the group consisting of PanAd1, PanAd2, PanAd3, ChAd55, ChAd73, ChAd83, ChAd146, ChAd147, ChAd3, ChAd4, ChAd5, ChAd6, ChAd7, ChAd8, ChAd9, ChAd10, ChAd11, ChAd16, ChAd17, ChAd19, ChAd20, ChAd22, ChAd24, ChAd26, ChAd30, ChAd31, ChAd37, ChAd38, ChAd44,1. Экспрессионная система, содержащая полинуклеотиды, кодирующие белки, причем экспрессирующая система включает первый полинуклеотид, кодирующий по мень
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充