Crystal Ronald G.,Hicks Martin J.,Rosenberg Jonathan B.,De Bishnu P.,Kaminsky Stephen M.,Davisson Robin L.
申请号:
US201314381534
公开号:
US10093947(B2)
申请日:
2013.02.25
申请国别(地区):
美国
年份:
2018
代理人:
Leydig, Voit & Mayer, Ltd.
摘要:
The invention is directed to an adeno-associated virus (AAV) vector which comprises a nucleic acid sequence encoding an antibody or antigen binding fragment that binds to nicotine or a nicotine analog. The invention also is directed to a composition comprising the AAV vector and methods of using the AAV vector to induce an immune response against nicotine in a mammal.