A system for coupling, uncoupling and controlling the operating parameters of the header assembly (32) on an agricultural harvesting machine, such as a combine (10). A fixed coupler block on the feeder assembly (25) of the combine is coupled with a movable coupler block (84) on the header assembly (32) to join hydraulic and electrical conduits (37, 38) by rotating a coupler handle (135) to lock the blocks together. As the handle rotates, it also causes push-pull cables (142, 143) to actuate latch pins(42, 443) which mechanically couple the header assembly (32) to the feeder assembly (25). The system (50) senses whether a header assembly (32) is present or not and, if present, what type of header assembly (32) is present. In the latter case, the system then controls the header related operating parameters of the combine and header assembly.