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PROCESS FOR PREPARING A MEDICAMENT
专利权人:
Norton Healthcare Ltd.
发明人:
Xian-Ming ZENG,Seah Kee TEE
申请号:
US15453940
公开号:
US20170172925A1
申请日:
2017.03.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides a process for preparing a particulate medicament that has greater homogeneity and a lower adhesion between the particles of the active ingredient and the carrier. The process comprises the steps of: (a) combining a pharmaceutically active ingredient in the form of an agglomerate of primary particles having an agglomerate particle size such that the agglomerate is capable of passing through a sieve having a mesh of 50-3000 .mu·m with a pharmaceutically acceptable particulate carrier, and (b) mixing the resultant material in a mixer to break up the agglomerate into primary particles dispersed in the pharmaceutically acceptable particulate carrier such that 90% or more of the pharmaceutically active ingredient exists as primary particles having a particle size of 50 .mu·m or less.
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