University of Washington through its Center for Commercialization
发明人:
Patrick S. Stayton,Anthony Convertine,Daniel M. Ratner,Selvi Srinivasan,Debobrato Das,Fang-Yi Su,Jasmin Chen,David Yee-Shawn Chiu,Daniel Douglas Lane
申请号：
US16381922
公开号：
US20190365906A1
申请日:
2019.04.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.
