An abuse deterrent pharmaceutical composition comprising a drug that is susceptible to abuse, a first acid soluble component, a first buffer component, and a delayed release buffer component. [Selection diagram] Figure 1乱用されやすい薬物と、第一の酸可溶性成分と、第一の緩衝成分と、そして遅延放出緩衝成分とを含む乱用抑止性医薬組成物。【選択図】図1