Mihee Hwang,Kukjin Park,Duckhyang Shin,Hyeon Lee,Sooin Kim,Eunyoung Cho,Misuk Kim,Dong Ho Ahn
申请号:
US14893571
公开号:
US10017743B2
申请日:
2014.06.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a novel MDCK-derived cell line capable of being suspension-cultured in a protein-free medium and a method for proliferating a virus using the MDCK-derived cell line to produce a vaccine. The novel MDCK-derived cell line exhibits high and uniform productivity for various viruses, while causing less viral antigenic variations with low tumorigenicity, and thus can be useful in producing viruses used for vaccines.