Adam Judge,Yun-Han Lee,Ian MacLachlan,Snorri S. Thorgeirsson
申请号：
US13497789
公开号：
US09222086B2
申请日:
2010.09.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides therapeutic nucleic acids such as interfering RNA (e.g., siRNA) that target the expression of genes associated with tumorigenesis and/or cell transformation, lipid particles (e.g., nucleic acid-lipid particles) comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles, e.g., for the treatment of a cell proliferative disorder such as cancer.
