The invention provides antibody-drug conjugates comprising an antibody conjugated to a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimer drug moiety via a linker, and methods of using the antibody-drug conjugates.本發明提供包含經由連接體與1-(氯甲基)-2,3-二氫-1H-苯并[e]吲哚(CBI)二聚體藥物部分結合之抗體的抗體-藥物結合物及使用該等抗體-藥物結合物之方法。
