FLYGARE, JOHN A.,PILLOW, THOMAS H.,SAFINA, BRIAN,VERMA, VISHAL,WEI, BINQING,DENNY, WILLIAM,GIDDENS, ANNA,LEE, HO,LU, GUO-LIANG,MILLER, CHRISTIAN,REWCASTLE, GORDON,TERCEL, MOANA,BONNET, MURIEL
申请号:
CA2918139
公开号:
CA2918139A1
申请日:
2014.06.16
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention provides antibody-drug conjugates comprising an antibody conjugated to a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimer drug moiety via a linker, and methods of using the antibody-drug conjugates.