James John Crawford,Daniel Fred Ortwine,Wendy B. Young
申请号：
US13667121
公开号：
US08722676B2
申请日:
2012.11.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Bicyclic piperazine compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
