CRAWFORD, JAMES JOHN,ORTWINE, DANIEL FRED,YOUNG, WENDY B.
申请号：
CA2852964
公开号：
CA2852964A1
申请日:
2012.11.02
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Bicyclic piperazine compounds of Formula (I) are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
