PROBLEM TO BE SOLVED: To provide a new low molecular compound which exhibits a calcium receptor antagonist action and can orally be administered in high safety.SOLUTION: There is provided a pharmaceutical composition containing a compound having general formula (I) (wherein, each substituent is defined as below: R1 and R2 are H or the like R3 is methyl, ethyl, or the like Z is carboxy Ar is phenyl or the like A is single bond or the like n is 0 or 1 and m is an integer of 0 to 6), or a pharmacologically acceptable salt thereof.COPYRIGHT: (C)2012,JPO&INPIT【課題】カルシウム受容体アンタゴニスト作用を示し、かつ安全性が高く経口投与が可能な新規な低分子化合物を提供することである。【解決手段】一般式(I)を有する化合物又はその薬理上許容される塩を含有する医薬組成物。【化1】[式中、各置換基は以下のように定義される。R1及びR2:水素原子等。R3:メチル基、エチル基等。Z:カルボキシ基。Ar:フェニル基等。A:単結合等。n:0又は1。m:0-6の整数。]【選択図】なし
