INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
发明人:
KIM, Jae-Min,김재민,KIM, Sung-Wan,김성완
申请号：
KRKR2016/005618
公开号：
WO2017/146305A1
申请日:
2016.05.27
申请国别(地区):
WO
年份:
2017
代理人:
摘要：
The present invention relates to a pharmaceutical composition for the treatment of depression accompanied by acute coronary syndrome. If a lipophilic statin according to the present invention is administered in combination with S-citalopram, the treatment effect against the depression that occurs after the acute coronary syndrome can increase about three times or more as compared with a single administration of the S-citalopram, which is commonly used as an antidepressant.La présente invention concerne une composition pharmaceutique pour le traitement de la dépression accompagnée dun syndrome coronarien aigu. Si une statine lipophile selon la présente invention est administrée en combinaison avec du S-citalopram, leffet thérapeutique contre la dépression intervenant après le syndrome coronarien aigu peut être multiplié par au moins environ trois par rapport à ce que lon observe avec la seule administration de S-citalopram, substance communément utilisée an tant quantidépresseur.본 발명은 급성관동맥증후군에 동반되는 우울증 치료용 약제학적 조성물에 관한 것이다. 본 발명에 따른 친유성 스타틴과 S-시탈로프람을 병용투여하면, 일반적으로 사용되고 있는 우울증 치료제인 S-시탈로프람 단독 투여시보다 약 3배 이상 급성관동맥증후군 후 발병되는 우울증에 대하여 치료 효과를 상승시킬 수 있는 효과가 있다.
