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有機化合物
专利权人:
ノバルティス アーゲー
发明人:
ダニエル・カスパル・ベーシュリン,ユルゲン・クラウス・マイバウム,ホルガー・ゼルナー
申请号:
JP2006540387
公开号:
JP4884230B2
申请日:
2004.11.25
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Disclosed are ´-amino-³-hydroxy-É-aryl-alkanoic acid amide compounds of formula (I) and the salts thereof, having renin-inhibiting properties. Also disclosed are pharmaceutical compositions comprising these compounds and methods of administering them for the treatment of hypertension, atherosclerosis, unstable coronary syndrome, congestive heart failure, cardiac hypertrophy, cardiac fibrosis, cardiomyopathy postinfarction, unstable coronary syndrome, diastolic dysfunction, chronic kidney disease, hepatic fibrosis, complications resulting from diabetes, such as nephropathy, vasculopathy and neuropathy, diseases of the coronary vessels, restenosis following angioplasty, raised intra-ocular pressure, glaucoma, abnormal vascular growth, hyperaldosteronism, cognitive impairment, alzheimers, dementia, anxiety states and cognitive disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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