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HUMAN INDUCED NEURONAL CELLS
专利权人:
Asa Abeliovich
发明人:
Asa Abeliovich,Liang Qiang
申请号:
US13980832
公开号:
US20140193341A1
申请日:
2012.01.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method for reprogramming a fibroblast into a human induced neuronal cell (hIN) is described. The method comprises expressing heterologous reprogramming factors Bm2, Myt11, Zic1, Olig2, Asc11 or any combination thereof, in said fibroblast, and culturing the fibroblast in a medium comprising BDNF, NT3, GeM or any combination thereof. Biomarkers describing the obtained hiN cells are also presented. In another aspect, methods for screening compounds using the hiN cells is described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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